Robert P. Kimberly, M.D.
Professor of Medicine and Microbiology
Director, UAB Division of Clinical Immunology and Rheumatology
University of Alabama at Birmingham
Dr. Kimberly is a distinguished expert in the field of Fc gamma
receptor polymorphisms research as applied to translational immunology.
He has made significant contributions in furthering our understanding
of the role of genetic factors and polymorphisms in the normal function
of the immune system and in the development of autoimmune diseases such
as systemic lupus erythematosus (SLE) and systemic vasculitis. Some of
his seminal contributions during his tenure at the Hospital for Special
Surgery, New York, include the demonstration of the impaired clearance
of immune complexes in SLE patients; characterization of the role of
FcG receptors in phagocytosis; and identification of the first human
lupus gene, FcGR-2A. Among his numerous professional memberships, Dr.
Kimberly chairs the Medical and Scientific Committee for the National
Office of the Arthritis Foundation.
Franklyn G. Prendergast, M.D., Ph.D.
Director
Mayo Clinic Center for Individualized Medicine
One of the key opinion leaders in the field of personalized medicine,
Dr. Prendergast is the Edmond and Marion Guggenheim Professor of
Biochemistry and Molecular Biology and Professor of Molecular
Pharmacology and Experimental Therapeutics at Mayo Medical School.
Previously he has served as the Director of Mayo Clinic Cancer Center.
He has held several other teaching positions at the Mayo Medical School
since 1975. Until recently Dr. Prendergast has served on the board of
trustees of the Mayo Foundation and the Mayo Clinic Board of Governors.
In addition, Dr. Prendergast serves as a Director at Eli Lilly.
Michael H. Shepard, Ph.D.
Founder,
Receptor Biologix, Inc.
Dr. Shepard has made significant contributions in the area of
development of targeted molecular therapies to treat cancer. While at
Genentech, he led the discovery and development of the breast cancer
antibody, Trastuzumab (Herceptin®), the first
target-directed cancer treatment for solid tumors. Dr. Shepard founded
Receptor BioLogix, a biopharmaceutical company focused on developing
Intron Fusion Proteins (IFP) to treat cancers and autoimmune diseases.
Until it got acquired by Symphogen, he served as the President and CSO
of the Company. Formerly, he was the CSO and Vice President of Research
at Canji, Inc., (acquired by Schering Plough), where he developed the
application of the p53 gene product for cancer treatment. For his
contributions to the development of the breast cancer therapy, Dr.
Shepard was awarded the prestigious Alpert Prize in 2006.
Jane E. Salmon, MD
Professor of Medicine
Co-Director, Mary Kirkland Center for Lupus Research
Hospital for Special Surgery
Dr. Salmon is the Collette Kean Research Professor and Director of the
Lupus Registry and Repository at Hospital for Special Surgery, and
Professor of Obstetrics and Gynecology at Weill Cornell Medical
College. Dr. Salmon’s basic and clinical studies have focused on
elucidating mechanisms of tissue injury in lupus and other autoimmune
diseases, pregnancy loss in women with lupus, and the determinants of
disease outcome in lupus patients with nephritis, pregnancy, and
cardiovascular disease. Some of her significant contributions include
identification of the first human non-MHC lupus gene, FcGR-2A;
characterization of the role of FcG receptors and their respective
polymorphisms in phagocytosis and pathogenesis of lupus and lupus
nephritis. Dr. Salmon has served on the Board of Directors of the
American College of Rheumatology and on the NIH Advisory Boards for the
North American Rheumatoid Arthritis Consortium and the Lupus Multiplex
Registry. She was a co-editor of Arthritis and Rheumatism. Dr. Salmon is the co-winner of the Carol-Nachman Prize for 2007 for her outstanding research contributions in rheumatology.
Mark C. Genovese, MD
Professor of Medicine
Co-Chief of the Division of Immunology and Rheumatology
Stanford University Medical Center
As the Director of the Center for Clinical Investigation, Dr. Genovese has
established a clinical research program that is focused on bench-to-bedside translational medicine in autoimmune diseases. He has
designed and participated in many investigator-initiated studies and
multi-center trials investigating targeted antibody and biological
therapies and therapeutic strategies for the treatment of autoimmune
diseases including rheumatoid arthritis. In addition, Dr. Genovese
collaborates with several other investigators on studies of biomarkers,
chemokines, cytokines, and cell surface markers associated with disease
progression and response to therapy. Dr. Genovese is an ad hoc
reviewer for numerous medical journals, and a board member of the
Stanford General Clinical Research Center. For his outstanding
independent contributions to clinical and basic research in
rheumatology, Dr. Genovese received The Henry Kunkel Young Investigator
Award from the American College of Rheumatology in 2008.